Sandra Oh, known for her role as Dr. Cristina Yang in Grey's Anatomy, stated that she has no intentions of returning to the show. She made this statement during the season two premiere party of Killing Eve, where she plays a British intelligence agent. Sandra described Killing Eve as her "home now" and plans to stay as long as the show will have her. Sandra won a Golden Globe and two Screen Actors Guild Awards for her role as Cristina Yang.

Grey's Anatomy is currently on its 15th season but has lost several original cast members over the years.